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Parallel Solution Phase Synthesis

Solution Phase Synthesis
Synthetic Organic Chemistry
Parallel Organic Synthesis in Solution Phase is widely used by the Synthetic Chemist to answer important research questions. Application areas include drug discovery, process development, polymers and petrochemicals. Chemists can choose from a wide range of existing reactions and employ statistical experimental design to enhance productivity and maximize data collection from precious starting materials.

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Products and Solutions
Parallel Synthesis: MiniBlock® and MiniBlock® XT Particle System Characterization: FBRM® and PVM® Automated Lab Reactors (ALR) and Reaction Calorimeters: RC1e™ and EasyMax™ In situ FTIR Reaction Analysis: ReactIR™ Software: iC and iControl™
Applications
Novel parallel synthesis of N-(4-oxo-2-substituted-4H-quinazolin-3-yl)-substituted sulfonamides
Emerging Technologies Supporting Chemical Process R&D and Their Increasing Impact on Productivity in the Pharmaceutical Industry
Incorporation of an Intramolecular Hydrogen-Bonding Motif in the Side Chain of 4-Aminoquinolines Enhances Activity against Drug-Resistant P. <i>falciparum</i>
A New Class of Blockers of the Voltage-Gated Potassium Channel Kv1.3 via Modification of the 4- or 7-Position of Khellinone
Solid-Phase Synthesis of Tetrahydro-1,4-benzodiazepine-2-one Derivatives as a â-Turn Peptidomimetic Library
Use of Quinolinium Salts in Parallel Synthesis for the Preparation of 4-Amino-2-alkyl-1,2,3,4-tetrahydroquinoline
Structure-Activity Relationship Study of Prion Inhibition by 2-Aminopyridine-3,5-dicarbonitrile-Based Compounds: Parallel Synthesis, Bioactivity, and in Vitro Pharmacokinetics
Parallel Synthesis of 3-Amino-4H-Quinolizin-4-ones, Fused 3-Amino-4H-Pyrimidin-4-ones, and Fused 3-Amino-2H-Pyran-2-ones
One-Step Synthesis of Oxazoline and Dihydrooxazine Libraries
Ionic Immobilization, Diversification, and Release: Application to the Generation of a Library of Methionine Aminopeptidase Inhibitors
Chemical Libraries via Sequential C-H Functionalization of Phenols
Application of Lean Manufacturing Concepts to Drug Discovery: Rapid Analogue Library Synthesis
Synthesis of a Polymer-Supported Anthracene and Its Application as a Dienophile Scavenger
Solution-Phase Parallel Synthesis of a Library of ¢2-Pyrazolines
Application of Solution-Phase Parallel Synthesis to Preparation of Trisubstituted 1,2,4-Triazoles
Solution-Phase Parallel Synthesis of Hexahydro-1H-isoindolone Libraries via Tactical Combination of Cu-Catalyzed Three-Component Coupling and Diels–Alder Reactions
Combinatorial Solution-Phase Synthesis in a 12-position MiniBlock with glass vessels
Polymer-supported reagents and scavengers to streamline tedious purification steps
The parallel synthesis of γ-turn-inspired peptidomimetic libraries in a MiniBlock XT
Solution Phase Synthesis Using a MiniBlock
LabMax Runs Continuous Process
The RC18 Automated Lab Reactor Performance versus RC1
The Small Scale Production System (SSPS): Production of High Value Compounds and Intermediates in the Kilo Scale