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MiniBlock

Webinars
Events

On Demand Webinar

Innovative Approaches for the Synthesis and Purification of Peptide Libraries

Carbon-carbon Coupling Reactions Using Silica Supported Catalysts for Reaction Screening and Library Generation

News

AutoChem Customer Community Site Version 2 Launched

The first automated chemistry development tool that requires no training

Overview
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Multifunctional synthesis platform

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All MiniBlock racks conform to microtiter plate size and shape, providing flexibility for collection, compatibility with dry down devices and ease of use. Using the microtiter plate footprint also keeps the overall system footprint small, making it automation friendly.

"Since using MiniBlocks^®, our labs report a 400% increase in new drug candidates and a 40% reduction in development time. MiniBlock is so widely accepted by our medicinal chemists that 70% of all current programs now use high-throughput chemistry", Dr. Harold Weller, Research Fellow, Bristol-Myers Squibb.

Business Information

Brochures

MiniBlock and MiniBlock XT: Maximize Productivity with Parallel Synthesis (pdf - 1 MB)

MiniBlock and MiniBlock XT Product Brochure (pdf - 1 MB)

Applications

Solid-Phase Synthesis of Tetrahydro-1,4-benzodiazepine-2-one Derivatives as a â-Turn Peptidomimetic Library

Construction of 6-Amino-2,2-Dimethyl-3,4,6-Trisubstituted-2H-1-Benzopyran Library by Solid Phase Synthesis

Application of Solution-Phase Parallel Synthesis to Preparation of Trisubstituted 1,2,4-Triazoles

Solid-Phase Synthesis of Urea and Amide Libraries Using the T2 Triazene Linker

Alternative Solvents for Elevated-Temperature Solid-Phase Parallel Synthesis. Application to Thionation of Amides

More Applications ...

Related Products

MiniBlock Application Notes

Optimization of the Ugi Reaction Using Parallel Synthesis and Liquid Handling (pdf - 380 KB)

Technical Information

Datasheets

Parallel Synthesis Productivity at an Affordable Price: MiniBlock XT-S and XT-S Plus (pdf - 2 MB)

Streamline Solids Processing with Parallel Filtration: MiniBlock (pdf - 208 KB)

Parallel Productivity for Solid Phase Peptide Synthesis (SPPS) (pdf)

Streamline Solids Processing with Parallel Filtration (pdf)

Manuals

MiniBlock Configuration Guide (pdf - 463 KB)

Videos

MiniBlock Video Library

Features and Benefits

The unique valve body design of the MiniBlock allows the opening and closing of all vessels at the same time. Supporting parts and accessories allow the following functionalities:

Reactions performed under inert atmosphere
Robust mixing via orbital shaking
Solvent dispensing
Resin and scavenger resin dispensing

MiniBlock reactors and supporting parts are also available in personal sets and synthesis packages, which result in cost savings. The personal set is configured around 2 MiniBlocks. Synthesis packages are configured around 6 MiniBlocks.

MiniBlock™ Product Introduction Seminar

Introduction to the MiniBlock™

Configurations, Agitation and Incubation, Product Collection

View the complete MiniBlock Video Library

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Parallel Synthesis: MiniBlock® and MiniBlock® XT
MiniBlock