Green Chemistry - Reducing sample sizes using automated dosing - METTLER TOLEDO

Green Chemistry - Reducing sample sizes using automated dosing

Green Chemistry - Reducing sample sizes using automated dosing

An extensive amount of waste is generated by sample preparation methods in analytical laboratories. Samples are usually prepared in 50ml or 100ml volumetric flasks, and even if several injections are made, only 100 µl of solution may be required. This means that more than 99.9% of prepared solutions are disposed of without ever being used.

As Green Chemistry becomes high profile and pressure mounts on the pharmaceutical industry to become more environmentally cognizant, how can we justify these methods?
Gravimetric sample preparation can be employed which has some key benefits. Reducing the quantities prepared has a significant impact on the amount of solvent and substance consumed, and the amount of waste generated during an analytical workflow. Weighing smaller amounts of sample can be achieved, whilst maintaining compliance with GLP/GMP and USP regulations, without risk to thequantos dosing systems green chemistry accuracy or confidence in the result.


Quantos dosing systems with automated powder and liquid dispensing support gravimetric sample preparation. Only the quantity required can be prepared in a small vial directly on the balance. No need to use volumetric flasks and prepare large amounts of sample or standard.

For more information, go to www.mt.com/qlb or www.mt.com/q-gsp.