For GMP labs subject to government regulation, regular pipette service
and calibration isn’t even a question. But what about non-GMP labs, such
as R&D? Wherever accuracy and repeatability of results matter, a
program for calibration and maintenance is the surest way to achieve and
maintain high-level pipetting performance with the fewest out-of-tolerance
failures.
Like any precision instrument, pipettes require regular servicing in order to maintain peak performance. They are comprised of a variety of mechanical parts that, like all things mechanical, wear out over time:
- In the case of pipettes, it is the seals that are most prone to wear. They usually perform for up to a year or more without leaking depending on pipette usage.
- Over time, shaft ends can get damaged especially when a high force or ‘banging’ occurs when mounting tips.
- Piston surfaces can deteriorate from shiny and clean to pitted especially when using aggressive or corrosive samples, leading to premature seal failure and pipette inaccuracy.
Leakage often starts gradually and may not be discovered until well after the accuracy and integrity of your research is compromised. However, a lab’s internal pipette failure rate can be significantly reduced via a program for regular maintenance and calibration.
Based on our extensive experience and under normal use, seals should be replaced at least once a year and shafts every year or so while pistons will provide good performance for at least several years before needing replacement.
METTLER TOLEDO offers a variety of calibration and preventive maintenance program options to suit all budgets and applications.
Services for Pipettes
http://www.mt.com/global/en/home/services/services/Pipette_Service_SBU.html