Seeding a Crystallization Process - METTLER TOLEDO

White Paper: Seeding a Crystallization Process

New Technologies for Crystallization Development


The white paper – Recent Advances for Seeding a Crystallization Process – discusses best practices for designing a seeding strategy and what parameters should be considered when implementing a seeding protocol. Although crystallization understanding has improved over the last thirty years, the seeding step still presents challenges when designing and developing new chemical processes.

This free white paper investigates how seeding has become one of the most critical steps in optimizing crystallization behavior and investigates how scientists can achieve this by:

  • Choosing seeding conditions
  • Identifying seed loading and size distribution
  • Seeding to control purity and optimize downstream separations
  • Advanced seeding techniques and feedback control