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FBRM® Technology

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On Demand Webinar

Monitoring Cell Count, Size and Shape in Fermentation Processes

Process Analytical Technology (PAT) Monitoring of Solid Dosage Formulations - Part II

Optimization of High Shear Wet Granulation

Top Five Ways To Improve Laboratory Crystallization

Real Time Control of Polymer Particle Size

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Real-Time Particle Size Analysis At Full Process Concentration

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Focused Beam Reflectance Measurement FBRM

Focused Beam Reflectance Measurement (FBRM®) provides the unique ability to measure particles and droplets in concentrated suspensions and emulsions – at full process concentration without the need for sample extraction and sample preparation.

FBRM G400 Technology

FBRM G400 Technology

Optimize Particle and Droplet Processes in Laboratory R&D

FBRM® G600L Technology

FBRM® G600L Technology

Optimize Laboratory Crystallization, Particle and Droplet Processes

FBRM® G600 Process Technology for Pilot/Production

FBRM® G600 Process Technology for Pilot/Production

Improve Production Processes For Pilot Plants and Manufacturing

FBRM® G600 Ex Process Technology for Hazardous Locations

FBRM® G600 Ex Process Technology for Hazardous Locations

Inline Measurement For ATEX and Class I, Div 1 Hazardous Environments

FBRM® C35 Technology

FBRM® C35 Technology

R&D, Scale-Up and Control of Granulation and Powder Processes

FBRM® Method of Measurement is based on a precise and sensitive measurement of the Chord Length Distribution that simultaneously tracks the rate and degree of change in particle count, dimension and shape. Probe-based FBRM® systems permit identical measurements while scaling up from the development laboratory to the pilot plant and to the manufacturing process.

FBRM® provides the ability to analyze particle and droplet systems at full process concentration without the need for sampling and off-line analysis.

Traditional offline particle size analysis has limited capabilities due to the difficulty of obtaining and preparing a representative sample. In addition, changes occurring between sampling and analysis can easily affect the properties that we are most interested in – including the concentration, size and shape of the particles or droplets. This is especially true in dynamic processes such as crystallization, flocculation, granulation and others where the particle system is changing considerably over the course of time. FBRM® was first developed and introduced by Lasentec® (Laser Sensor Technology Corporation) in 1986, at which time it won a coveted R&D100 prize for its innovative design allowing measurement of particles in concentrated suspensions and slurries – without the need for sampling and dilution.

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