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Crystals, Particles, and Droplets: Measurement for Real-Time Optimization
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FBRM® and PVM® technologies and expertise enable scientists and engineers to use real-time particle and droplet distribution measurement to make more informed, faster decisions. Knowledge of particle performance gained through FBRM® and PVM® technologies can cut months from development times, maximize process throughput, and optimize product quality. The application of FBRM® and PVM® ensures targeted particle distributions are achieved, robust repeatable processes are designed, downstream cycle times are maximized, and failures at pilot and manufacturing scale are eliminated. FBRM® and PVM® systems are available for every development stage from lab through scale-up and process, ensuring consistent data throughout the life of a process.
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| FBRM® and PVM® Products for the Lab | |||
| Model | Technology | Vessel Size | Key Characteristic |
S400A![]() | FBRM® | 30ml-500ml | Portable |
S400E![]() | FBRM® | 30ml-500ml | For use with D600L |
S400Q![]() | FBRM® | 30ml-500ml | Multiple probes |
D600L![]() | FBRM® | 500ml-5L | Results scalable to plant |
V819![]() | PVM® | 250ml-5L | In-process video microscopy |
FBRM C35![]() | FBRM® | 5L+ Granulator/Fluid Bed | Patent Pending Scraper ensures clean window in dry or moist environments |
| FBRM® Products for Process | |||
| Model | Technology | Vessel Size | Key Characteristic |
D600R![]() | FBRM® | 1L+ | Dip-pipe mountable |
D600S/T![]() | FBRM® | 1L+ | Pipeline installations |
D600P![]() | FBRM® | 20L+ | 1m probe length |
D600X![]() | FBRM® | 1L+ | Customizable |
FBRM C35![]() | FBRM® | 5L+ Granulator/Fluid Bed | Patent Pending Scraper ensures clean window in dry or moist environments |
| iC FBRM™ Software: Effective Lasentec® Data Analysis |
After purchasing Lasentec® in 2001, METTLER TOLEDO has become the world leader for in-line particle/droplet size, shape, and count characterization.











