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|On Demand Webinar|| Roller Compaction Process Optimization Using At-Line Particle Characterization |
One goal of roller compaction is to improve compressibility and yield repeatable tablet dissolution and content uniformity. To ensure downstream process and product consistency, a successful roller compaction process establishes a continuous flow with a consistent particle size distribution. However, inconsistencies often occur during dry granulation scale-up due to changing raw materials or process dynamics such as segregation, compaction force, and flow properties.
|On Demand Webinar|| Bottling & Filling of Substances for Commercial Use and Internal Reference |
In the current global climate, all companies and industries are looking for ways to increase their productivity and reduce their costs. For manufacturers and distributors of fine chemicals, reference materials and standards and particularly those who are concerned with bottling, filling and repackaging of small quantities of chemicals (e.g. 1mg -250mg), there is an automated powder dosing solution that will revolutionise your processes.
|On Demand Webinar|| Enhancing safety in the workplace: Automated powder dosing of hazardous compounds |
There is a great awareness within the pharmaceutical industry regarding the hazards involved in handling active drug compounds. One specific hazard is that of exposure to airborne contaminants, encountered during dispensing and handling procedures due to the way in which the analyst works with a balance. Automated powder dosing offers superior protection for the analyst compared to manual dosing.
|On Demand Webinar|| Reducing Out-of-Specification Results in QA/QC |
Weighing out powders to prepare samples and standards for analytical methods such as HPLC can be a time-consuming task with high error risk. With the advent of faster analytical methods, such as UHPLC, and rapid advances in software developments providing faster data processing, attention is once again focussing on sample preparation as the bottleneck in the process.
|On Demand Webinar|| Streamline your powder dosing |
There are many stages in the drug discovery process where powder dosing is required, in varying target amounts and batch sizes, and into a wide range of different target containers. As new drugs become more effective and more potent, there are also greater risks for the people who are exposed to these compounds during development and formulation. Mettler Toledo’s Quantos automated powder dosing technology has been successfully applied to capsule filling, commercial bottling/filling and QA/QC applications. See how Quantos can improve these processes in terms of quality, productivity and user safety, ultimately saving time and money.
|On Demand Webinar|| Building Green Pharmaceutical Manufacturing on a Foundation of PAT and QbD |
|On Demand Webinar|| Quick and easy capsule filling for pre-clinical and clinical trials |
The first step in preparation of pre-clinical and clinical trials is manually weighing in highly potent, hazardous substances precisely with a spatula. This webinar looks at the real practicalities of capsule filling, with a focus on the requirements for use in pre-clinical and clinical phase 0 and 1 trials, and introduces a quick, easy and precise automated solution.
|On Demand Webinar|| A unique workflow for linearity testing using automated sample preparation and UHPLC |
When validating a method according to the ICH guidelines, it is necessary to perform a linearity experiment. This requires the preparation of multiple calibration levels, analysis of the samples by liquid chromatography, and calculation/reporting of the results. Each of these steps can be very time consuming, and in many cases error prone. This is especially true if the analytical method being tested requires the measurement of multiple components.
|On Demand Webinar|| WeighCom Application – Improving Mass Determination Processes |
To ensure reliable and correct data generation, Mettler Toledo offers the WeighCom application, which is installed on all manual mass comparators of the XP and AX lines. This webinar will discuss physical effects as well as the data security topic.
|On Demand Webinar|| Preventing Costly Out-of-Specification Investigations |
Sample preparation is now reported to be the most time-consuming, labor-intensive and error-prone part of the workflow, with some 50% of OOS errors attributed to sample processing steps and human error.