Peptide libraries are widely investigated and routinely screened for their drug-like properties. Synthesis using resins or solid supports is a favorite route for researchers performing peptide synthesis. However, synthesis and subsequent purification are major bottlenecks encountered during synthesis of peptide libraries. This webinar examines challenges related to the synthesis of peptide libraries and will discuss various applications including the synthesis of cyclic peptides employing a unique safety-catch linker, which enables the production of diverse libraries for biological screening.
A unique strategy involving functionalized solid supported reagents followed by purification with ion exchange resins to produce libraries of pure dipeptides will also be presented.
Related topics: synthesis, parallel synthesis, peptides, cyclic peptides, peptide libraries, functionalized reagents, solid phase synthesis, ion exchange resin, coupling reagents, Fmoc, tBoc, solid phase peptide synthesis
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