All in situ optical characterization techniques risk a slight degree of probe fouling in concentrated solid suspensions. Fouling is compounded by supersaturation which occurs during crystallization and precipitation. Even when fouling is slight (1% of the probe window) optical measurement results are often skewed to the point where they are misleading and confusing. When this occurs data analysis is difficult, time consuming, and may result in costly incorrect conclusions or repeat experiments.
Three case studies are presented in this webinar:
- Identify Multiple Nucleation Events During Anti-Solvent Addition
- Understanding Particle Agglomeration Following Rapid Precipitation
- Optimizing Seeded Crystallization by Understanding Growth Mechanism
Benjamin Smith is a Chemical Engineer dedicated to the use of inline particle characterization technologies for the development, scale-up and manufacturing of processes. As a result, (bio) pharma, chemical and food companies bring products to market faster, at lower costs and with higher quality. Benjamin is currently a Market Manager at METTLER TOLEDO.