The ReactIR™ flow cell is presented as a convenient inline analytical tool for continuous flow chemistry processing. The flow cell, operated with ATR technology, is attached inline using standard Omnifit® connections. With the established iC IR 4.0 software the consumption of reagents and formation of products can be monitored in real-time, allowing for rapid optimization. Unstable reactive intermediates can also be observed in situ, giving mechanistic insight to complex transformations.
English
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German
This webinar will deal with the application of the ReactIR™ flow cell inline using various meso and micro scale flow chemistry equipment. The utility of the cell for a range of different reaction types will be presented:
- Curtius rearrangement using the Vapourtec R2+/R4
- Butane-2,3-diacetal protection using the Uniqsis FlowSyn
- Hydrogenation using the H-Cube Midi™
- Marshall reaction using Future Chemistry microfluidic devices
Guest Presenters
Steven V. Ley
Steven V. Ley is the BP (1702) Professor of Chemistry at the University of Cambridge. He received his Ph.D. degree from Loughborough University in 1972, after which he carried out postdoctoral research with Leo Paquette and Derek H. R. Barton. He was appointed to the staff at Imperial College in 1975 and became head of department in 1989. He was elected to the Royal Society (London) in 1990 and moved to Cambridge in 1992. He was President of the Royal Society of Chemistry (2000–2002) and was made a CBE in January 2002. His work of over 670 publications has been recognized by several prestigious prizes and awards, including most recently the 2009 Tetrahedron Prize.
Heiko Lange
Heiko Lange, born in Lüdenscheid (Germany), studied Chemistry at the University of Münster in Germany and completed his undergraduate studies in 2004 with a diploma in chemistry under the supervision of Professor Dieter Hoppe. Having finished his Ph.D. in the same group, he started his postdoctoral research in 2008 in the group of Professor Steven V. Ley. His current research interests are complex natural product synthesis using modern techniques and the development of new polymer-supported reagents in order to further simplify synthetic procedures.
Catherine F. Carter
Catherine F. Carter received an MSci in Chemistry from the University of Nottingham (2004-2008). She completed her final year project with Professor Chris Hayes and is currently a Ph.D. student in Professor Ley’s research group working towards the application of new technologies to organic synthesis.
Related topics: Attenuated Total Reflection, ATR, continuous processing, continuous chemistry, flow chemistry, ReactIR™, in situ reaction analysis, FTIR, organic chemistry, in situ reaction spectroscopy, flow cell, iC IR, meso scale, micro scale, hydrogenation, synthetic chemistry, organic synthesis, ReactIR™ 45m, reaction analysis software, curtius rearrangement, marshall reaction, Royal Society of Chemistry, organic synthesis, polymer
Related topics: Attenuated Total Reflection, ATR, continuous processing, continuous chemistry, flow chemistry, ReactIR™, in situ reaction analysis, FTIR, organic chemistry, in situ reaction spectroscopy, flow cell, iC IR, meso scale, micro scale, hydrogenation, synthetic chemistry, organic synthesis, ReactIR™ 45m, reaction analysis software, curtius rearrangement, marshall reaction, Royal Society of Chemistry, organic synthesis, polymer