METTLER TOLEDO is pleased to be sponsoring the Process Analytical Sessions at FACSS/SCiX 2012 and presenting during the "What's Hot" section at 4:30PM in Exhibit Hall B:
Understanding the Challenges: Implementing Inline FTIR Analysis with ReactIR™ 45P – Wes Walker
In the chemical, pharmaceutical, and allied industries, tremendous benefits can be derived from inline FTIR analyses. These benefits include rapid determination of endpoint, reduction or even elimination of sampling, the ability to trend concentrations of chemical species that do not lend themselves to offline analyses, data-dense trend-lines that assist in process understanding and control and ease of unattended and automatic analysis and data logging. For a properly chosen process, the acquisition of infrared spectra is an exercise that can lead to a dramatic return on investment. However, there are challenges that must be overcome that are associated with the plant setting. When these challenges are not considered and prepared for carefully, there is a heightened risk that inline analysis will not be viewed as successful by all of the stakeholders in the production environment. Preparation for these challenges is the key. This presentation will focus on the selection of the right chemical process as well as hardware, software, and ancillary equipment advances that enable the user to implement inline FTIR successfully.
METTLER TOLEDO is the world leader in in situ spectroscopy technology and provides tools to continuously monitor chemical reactions for a deeper understanding of reaction kinetics, mechanisms and pathways. Our in situ FTIR reaction analysis technologies provide real-time composition analysis to monitor key reaction species without the need for grab sampling. Real-time in situ reaction monitoring offers the maximum amount of reaction information with the minimum amount of effort.
Spectroscopy technology on display:
- ReactIR™ for the lab is ideal for organic synthesis, process development and as a PAT tool to measure and understand reaction progression, initiation, conversion, intermediates and endpoint. ReactIR™ can determine if the desired reaction occurred and provide associated endpoint determination.
- ReactIR™ for scale-up studies, campaigns and production monitoring provides non-destructive, rapid, quantitative chemical analysis of key reaction components. ReactIR™ supports the design of safe, robust processes that build quality into the commercial process enabling consistency and repeatability and eliminating failures.
White Paper – Metal Catalyzed Transformations
This white paper shows how in situ IR spectroscopy is used to uncover key parameters in chemical investigations. Accurately determining the start and end point of reactions, as well as obtaining sufficient information to fully understand, characterize and optimize reactions is a major challenge. This, combined with the need to complete more investigations, with less resource and time, is leading researchers to look for innovative ways to gain this information.