Solid Phase Peptide Synthesis (SPPS)

Peptides are synthesized for a variety of application areas and research interests. Peptide synthesis application areas include array or library synthesis, synthesis of peptides for biological or screening assays, and screening of reaction conditions. Solid Phase Peptide Synthesis (SSPS) is a favorite route for peptide synthesis.

SPPS is used for interesting applications like synthesis of cyclic peptide, polypeptide libraries, synthesis of peptide mimetics and libraries of protease substrates. Screening of reaction conditions like coupling times, concentration of reagents, in situ neutralizations, or optimization of high value synthetic processes is also possible. Parallel synthesis of peptide libraries is an acceptable alternative to conventional techniques like SPOT synthesis.

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Solid Phase Peptide Synthesis Abstracts